Oct 03, 2024

Company / Press Release

Active Chlorine Component of Hypochlorous Acid Solution Volatilized in the Air(*1) Suppresses Over 99% of Canine Distemper Viruses and Feline Herpesviruses

- Effects on viruses in a space of approx. 25 m3

Osaka, Japan – Panasonic Corporation (https://www.panasonic.com/global/home.html) today announced that its Heating & Ventilation A/C Company (hereinafter referred to as Panasonic) verified that the active chlorine component volatilized from the hypochlorous acid solution, produced by electrolysis of salt water, effectively suppresses over 99% of canine distemper viruses and feline herpesviruses that have adhered to test samples in a space of approx. 25 m3 within 120 minutes.(*2)

The hypochlorous acid solution is produced through the electrolysis of salt water and demonstrates high efficacy in sterilization and deodorization. Since adopting the hypochlorous acid solution for the hygiene maintenance system of cup-dispensing vending machines in 1987,(*3) Panasonic has been researching hypochlorous acid technology for over 30 years. The company verified in the past few years that the solution is effective in suppressing viruses, including canine parvoviruses, feline panleukopenia viruses, and feline coronaviruses.

Canine distemper viruses, which mainly affect dogs, are highly contagious and can also infect other wild animals. They are transmitted through airborne droplets, direct contact, or via the body fluids and excrement of infected animals. Early symptoms include fever, sneezing, coughing, a runny nose, and eye inflammation. As the condition progresses, digestive symptoms (diarrhea, vomiting) and neurological symptoms (convulsions, paralysis) may appear, potentially leading to fatal consequences in severe cases.
On the other hand, feline herpesviruses infect felines, primarily affecting their respiratory system. They are transmitted through airborne droplets and direct contact, causing early symptoms such as sneezing, a runny nose, eye discharge, and conjunctivitis. In severe cases, they can develop symptoms, including fever, loss of appetite, stomatitis, and respiratory difficulty.

Based on the current verification results, the active chlorine component volatilized from the hypochlorous acid solution is expected to have suppressive effects on canine distemper viruses and feline herpesviruses that have adhered to floors, examination and operating tables for pets, and other surfaces.

■Verification method
Two cases were verified: one by soaking the rotary sterilization filter in a hypochlorous acid solution of approx. 100 mg/L, exposing the filter to a given amount of wind (3.8 m3/min) to volatilize the active chlorine component, and then exposing the specimens with canine distemper viruses and feline herpesviruses to the volatilized substance; and the other by not exposing the specimens to the active chlorine component (natural attenuation).

■Verification results
The effect of suppressing 99% or more of the canine distemper viruses within 120 minutes was confirmed (Figure 1). The effect of suppressing 99% or more of the feline herpesviruses within 120 minutes was confirmed (Figure 2).

[Figure 1. Infectivity titer of viruses by time elapsed
(Canine distemper viruses)]

[Figure 2. Infectivity titer of viruses by time elapsed
(Feline herpesviruses)]

*1: Solution made by electrolysis of salt water

*2: These verifications were conducted for basic research purposes and did not involve any products containing the hypochlorous acid solution.

*3: Including the SANYO Electric era

[Details of Verification]

External view of the test chamber measuring 25 m3

  • Verifying organization: Panasonic Corporation
    Testing organization: Kitasato Research Center for Environmental Science
  • Verification device: The rotary sterilization filter was soaked in a hypochlorous acid solution of approx. 100 mg/L and was exposed to a specified amount of wind (3.8 m3/min) to volatilize the active chloride component.
  • Verification method
    • Exposure time: 0 to 5 hours (Exposure [with the verification device] / Non-exposure [no verification devices])
    • Test space volume
    Exposure: Approx. 25 m3 without ventilation
    Non-exposure (natural attenuation): Approx. 25 m3 without ventilation

[Placement of viruses (exposure)]
• Placement of the samples to which canine distemper viruses and feline herpesviruses have adhered
Drop a specified amount(*4) of test virus liquid onto each petri dish, and air-dry the liquid for about 20 minutes in a desiccator(*5) containing silica gel. Place the petri dishes with the test viruses 1.5 m away from the verification device (1.2 m above the floor).

*4: Canine distemper viruses: 2 μL x 15 spots (total 30 μL)

: Feline herpesviruses: 2 μL x 5 spots (total 10 μL)

*5: Airtight container with desiccant inside

[Placement of viruses (non-exposure)]
• Place petri dishes with canine distemper viruses and feline herpesviruses in a test room of approx. 25 m3.

  • Exposure method
    Place specimens with canine distemper viruses and feline herpesviruses in a test room of approx. 25 m3, and then operate the verification device.
    • Measurement of canine distemper viruses
    Collected petri dishes at each predetermined time. Used the liquid used to wash the dishes as an undiluted test solution, and serially diluted it to 10 levels. Infected cells with the undiluted test solution or diluted solution, applied the necessary treatment, and then incubated them in a CO2 incubator for the specified period.(*6) Observed the CPE produced by the proliferation of the viruses under a microscope, and determined the virus infectivity titer (TCID50/mL) using the Reed-Muench method. This test measured the infectivity titer per mL of the liquid washed out from each test piece (TCID50/test piece) for determination.

*6: Canine distemper viruses: 7 days

: Feline herpesviruses: 6 days

[Sterilization Effects of Hypochlorous Acid: Overview of Verification related to dogs and cats]

Target

Verification method

Verification body

Year of verification

Canine parvovirus

Contact with gases

Kitasato Research Center for Environmental Science

2019

Feline panleukopenia virus

Contact with gases

Kitasato Research Center for Environmental Science

2019

Feline coronavirus

Contact with gases

Kitasato Research Center for Environmental Science

2020

Distemper virus

Contact with gases

Kitasato Research Center for Environmental Science

2024

Herpesvirus

Contact with gases

Kitasato Research Center for Environmental Science

2024

About Panasonic Corporation

Panasonic Corporation offers products and services for a variety of living environments, ranging from homes to stores to offices and cities. There are five businesses at the core of Panasonic Corporation: Living Appliances and Solutions Company, Heating & Ventilation A/C Company, Cold Chain Solutions Company, Electric Works Company and China and Northeast Asia Company. The operating company reported consolidated net sales of 3,494.4 billion yen for the year ended March 31, 2024. Panasonic Corporation is committed to fulfilling the mission of Life Tech & Ideas: For the wellbeing of people, society and the planet, and embraces the vision of becoming the best partner of your life with human-centric technology and innovation. Learn more about Panasonic: https://www.panasonic.com/global/about/

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Issued:
Panasonic Corporation

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